Feasibility of a tapering opioids prescription program for trauma patients at high risk of chronic consumption (TOPP-trauma): protocol for a pilot randomized controlled trial

Abstract Background Opioid use disorder (OUD) and deaths related to the chronic use of opioids have increased significantly over the last two decades.Chronic consumption of opioids has been documented in many patients with traumatic injuries.Preliminary research findings have shown that interventions using cognitive-behavioral strategies were a pro

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The protective role of brown adipose tissue in cardiac cell damage after myocardial infarction and heart failure

Abstract Acute myocardial infarction (AMI) and related cardiovascular disease complications are the leading causes of mortality worldwide.Brown adipose tissue (BAT) is thermogenic and characterized by the uncoupling protein expression.Recent studies have found that in cardiovascular diseases, activated BAT can effectively Heat Management Device imp

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Investigation on the Reduced-Order Model for the Hydrofoil of the Blended-Wing-Body Underwater Glider Flow Control with Steady-Stream Suction and Jets Based on the POD Method

The rapid acquisition of flow field characterization information is crucial for closed-loop active flow control.The proper orthogonal decomposition (POD) method is a widely used flow field downscaling modeling Storage Basket method to obtain flow characteristics effectively.Based on the POD method, a flow field reduced-order model (ROM) is construc

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